Title : Regulating Retinoic Acid Availability during Development and Regeneration: The Role of the CYP26 Enzymes.

Pub. Date : 2020 Mar 5

PMID : 32151018






11 Functional Relationships(s)
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1 Regulating Retinoic Acid Availability during Development and Regeneration: The Role of the CYP26 Enzymes. Tretinoin cytochrome P450 family 26 subfamily A member 1 Homo sapiens
2 This review focuses on the role of the Cytochrome p450 subfamily 26 (CYP26) retinoic acid (RA) degrading enzymes during development and regeneration. Tretinoin cytochrome P450 family 26 subfamily A member 1 Homo sapiens
3 This review focuses on the role of the Cytochrome p450 subfamily 26 (CYP26) retinoic acid (RA) degrading enzymes during development and regeneration. Tretinoin cytochrome P450 family 26 subfamily A member 1 Homo sapiens
4 This review focuses on the role of the Cytochrome p450 subfamily 26 (CYP26) retinoic acid (RA) degrading enzymes during development and regeneration. Tretinoin cytochrome P450 family 26 subfamily A member 1 Homo sapiens
5 This review focuses on the role of the Cytochrome p450 subfamily 26 (CYP26) retinoic acid (RA) degrading enzymes during development and regeneration. Tretinoin cytochrome P450 family 26 subfamily A member 1 Homo sapiens
6 Cyp26 enzymes, along with retinoic acid synthesising enzymes, are absolutely required for RA homeostasis in these processes by regulating availability of RA for receptor binding and signalling. Tretinoin cytochrome P450 family 26 subfamily A member 1 Homo sapiens
7 Cyp26 enzymes, along with retinoic acid synthesising enzymes, are absolutely required for RA homeostasis in these processes by regulating availability of RA for receptor binding and signalling. Tretinoin cytochrome P450 family 26 subfamily A member 1 Homo sapiens
8 Cyp26 enzymes, along with retinoic acid synthesising enzymes, are absolutely required for RA homeostasis in these processes by regulating availability of RA for receptor binding and signalling. Tretinoin cytochrome P450 family 26 subfamily A member 1 Homo sapiens
9 Cyp26 enzymes are necessary to generate RA gradients and to protect specific tissues from RA signalling. Tretinoin cytochrome P450 family 26 subfamily A member 1 Homo sapiens
10 Cyp26 enzymes are necessary to generate RA gradients and to protect specific tissues from RA signalling. Tretinoin cytochrome P450 family 26 subfamily A member 1 Homo sapiens
11 Here, the function of CYP26 enzymes is discussed in the context of the RA signalling pathway, enzymatic structure and biochemistry, human genetic disease, and function in development and regeneration as elucidated from animal model studies. Tretinoin cytochrome P450 family 26 subfamily A member 1 Homo sapiens