Title : Comparative Interactome Analysis of Emerin, MAN1 and LEM2 Reveals a Unique Role for LEM2 in Nucleotide Excision Repair.

Pub. Date : 2020 Feb 18

PMID : 32085595






1 Functional Relationships(s)
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Protein Name
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1 Accordingly, LEM2-depleted cells, but not MAN1- and emerin-depleted cells, showed impaired proliferation following ultraviolet-C (UV-C) irradiation and prolonged accumulation of gammaH2AX, similar to cells deficient in the nucleotide excision repair protein DNA damage-binding protein 1 (DDB1). gammah2ax LEM domain nuclear envelope protein 2 Homo sapiens