Title : MiR-129-5p promotes docetaxel resistance in prostate cancer by down-regulating CAMK2N1 expression.

Pub. Date : 2020 Feb

PMID : 31876385






7 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 MiR-129-5p promotes docetaxel resistance in prostate cancer by down-regulating CAMK2N1 expression. docetaxel microRNA 1295a Homo sapiens
2 This study focuses on the effect of miR-129-5p on docetaxel-resistant (DR) prostate cancer (PCa) cells invasion, migration and apoptosis. docetaxel microRNA 1295a Homo sapiens
3 Involved molecular mechanism studies revealed that miR-129-5p reduced downstream CAMK2N1 expression to further impact on chemoresistance to docetaxel of PCa cells, indicating its vital role in PCa docetaxel resistance. docetaxel microRNA 1295a Homo sapiens
4 Involved molecular mechanism studies revealed that miR-129-5p reduced downstream CAMK2N1 expression to further impact on chemoresistance to docetaxel of PCa cells, indicating its vital role in PCa docetaxel resistance. docetaxel microRNA 1295a Homo sapiens
5 Our findings revealed that miR-129-5p contributed to the resistance of PC-3-DR cells to docetaxel through suppressing CAMK2N1 expression, and thus targeting miR-129-5p may provide a novel therapeutic approach in sensitizing PCa to future docetaxel treatment. docetaxel microRNA 1295a Homo sapiens
6 Our findings revealed that miR-129-5p contributed to the resistance of PC-3-DR cells to docetaxel through suppressing CAMK2N1 expression, and thus targeting miR-129-5p may provide a novel therapeutic approach in sensitizing PCa to future docetaxel treatment. docetaxel microRNA 1295a Homo sapiens
7 Our findings revealed that miR-129-5p contributed to the resistance of PC-3-DR cells to docetaxel through suppressing CAMK2N1 expression, and thus targeting miR-129-5p may provide a novel therapeutic approach in sensitizing PCa to future docetaxel treatment. docetaxel microRNA 1295a Homo sapiens