Title : Sensing of nutrients by CPT1C regulates late endosome/lysosome anterograde transport and axon growth.

Pub. Date : 2019 Dec 23

PMID : 31868590






3 Functional Relationships(s)
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1 We demonstrate in HeLa cells that carnitine palmitoyltransferase 1C (CPT1C) senses malonyl-CoA and enhances LE/Lys anterograde transport by interacting with the endoplasmic reticulum protein protrudin and facilitating the transfer of Kinesin-1 from protrudin to LE/Lys. pentalysine zinc finger FYVE-type containing 27 Homo sapiens
2 We demonstrate in HeLa cells that carnitine palmitoyltransferase 1C (CPT1C) senses malonyl-CoA and enhances LE/Lys anterograde transport by interacting with the endoplasmic reticulum protein protrudin and facilitating the transfer of Kinesin-1 from protrudin to LE/Lys. pentalysine zinc finger FYVE-type containing 27 Homo sapiens
3 We demonstrate in HeLa cells that carnitine palmitoyltransferase 1C (CPT1C) senses malonyl-CoA and enhances LE/Lys anterograde transport by interacting with the endoplasmic reticulum protein protrudin and facilitating the transfer of Kinesin-1 from protrudin to LE/Lys. pentalysine zinc finger FYVE-type containing 27 Homo sapiens