Title : Therapeutic potential of functionalized siRNA nanoparticles on regression of liver cancer in experimental mice.

Pub. Date : 2019 Nov 1

PMID : 31676815






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1 In the present study, an effective, safe and biocompatible survivin siRNA encapsulated, GalNAc decorated PEGylated PLGA nanoconjugates (NCs) viz., GalNAc@PEG@siRNA-PLGA were engineered and their synergistic antitumor efficacy was evaluated for targeted delivery in HCC bearing experimental mice. plga baculoviral IAP repeat-containing 5 Mus musculus