Pub. Date : 1988 Sep
PMID : 3166490
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Effects of acute ethanol administration on the hepatic xanthine dehydrogenase/oxidase system in the rat. | Ethanol | xanthine dehydrogenase | Rattus norvegicus |
| 2 | Incubation of acetaldehyde with rat liver supernatant at 37 degrees C converted xanthine dehydrogenase to xanthine oxidase in a dose-dependent manner, whereas incubation of ethanol with rat liver supernatant did not lead to conversion. | Acetaldehyde | xanthine dehydrogenase | Rattus norvegicus |
| 3 | These data suggest that biotransformation of ethanol is required for conversion of hepatic xanthine dehydrogenase to xanthine oxidase. | Ethanol | xanthine dehydrogenase | Rattus norvegicus |
| 4 | Because xanthine oxidase utilizes molecular oxygen to produce superoxide radical, ethanol-induced conversion of xanthine dehydrogenase to xanthine oxidase could contribute to the enhanced lipid peroxidation reported previously after administration of a single dose of ethanol. | Oxygen | xanthine dehydrogenase | Rattus norvegicus |
| 5 | Because xanthine oxidase utilizes molecular oxygen to produce superoxide radical, ethanol-induced conversion of xanthine dehydrogenase to xanthine oxidase could contribute to the enhanced lipid peroxidation reported previously after administration of a single dose of ethanol. | Superoxides | xanthine dehydrogenase | Rattus norvegicus |
| 6 | Because xanthine oxidase utilizes molecular oxygen to produce superoxide radical, ethanol-induced conversion of xanthine dehydrogenase to xanthine oxidase could contribute to the enhanced lipid peroxidation reported previously after administration of a single dose of ethanol. | Ethanol | xanthine dehydrogenase | Rattus norvegicus |
| 7 | Because xanthine oxidase utilizes molecular oxygen to produce superoxide radical, ethanol-induced conversion of xanthine dehydrogenase to xanthine oxidase could contribute to the enhanced lipid peroxidation reported previously after administration of a single dose of ethanol. | Ethanol | xanthine dehydrogenase | Rattus norvegicus |