Title : Reoxygenation injury in isolated hepatocytes: cell death precedes conversion of xanthine dehydrogenase to xanthine oxidase.

Pub. Date : 1988 Aug 30

PMID : 3166376






1 Functional Relationships(s)
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1 The results suggest that in the intact organ participation of reactive oxygen species, generated by xanthine oxidase, in reoxygenation injury may only occur when, upon reoxygenation, hypoxic cell injury in part of the tissue has progressed to such an extent that there is a significant conversion of xanthine dehydrogenase to xanthine oxidase. Reactive Oxygen Species xanthine dehydrogenase Rattus norvegicus