Title : Biochemical properties of a highly purified v-rasH p21 protein overproduced in Escherichia coli and inhibition of its activities by a monoclonal antibody.

Pub. Date : 1985 Jun

PMID : 3162096






3 Functional Relationships(s)
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Protein Name
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1 The purified p21 possesses full biochemical activities of GTP/GDP binding, autokinase, and GTPase. Guanosine Triphosphate cyclin-dependent kinase inhibitor 1A (P21) Mus musculus
2 The purified p21 possesses full biochemical activities of GTP/GDP binding, autokinase, and GTPase. Guanosine Diphosphate cyclin-dependent kinase inhibitor 1A (P21) Mus musculus
3 We found that only one monoclonal antibody, Y13-259, was capable of inhibiting both GTP/GDP binding and autokinase enzymatic activities, suggesting that these p21 activities are related activities conferred by a single active center within the p21 molecule. Guanosine Triphosphate cyclin-dependent kinase inhibitor 1A (P21) Mus musculus