Title : Pharmacological inhibition of glycogen synthase kinase 3 increases operant alcohol self-administration in a manner associated with altered pGSK-3β, protein interacting with C kinase and GluA2 protein expression in the reward pathway of male C57BL/6J mice.

Pub. Date : 2020 Feb

PMID : 31503067






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Given prior results showing that AMPA receptor activity regulates alcohol self-administration, we propose that signaling through the GSK-3/PICK1/GluA2 molecular pathway drives the positive reinforcing effects of the drug, which are required for abuse liability. Alcohols protein interacting with C kinase 1 Mus musculus