Title : [Is there a correlation between sugar content, thrombocyte aggregating activity and molecular size of factor VIII?].

Pub. Date : 1979 Sep 29

PMID : 314662






3 Functional Relationships(s)
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1 Staining of disulfide-reduced factor VIII subunits, in polyacrylamide gels, with galactose-specific fluorescein-labelled Ricinus communis lectins, showed an increased binding affinity with increasing size and von Willebrand activity of the parent factor VIII. Galactose coagulation factor VIII Bos taurus
2 Staining of disulfide-reduced factor VIII subunits, in polyacrylamide gels, with galactose-specific fluorescein-labelled Ricinus communis lectins, showed an increased binding affinity with increasing size and von Willebrand activity of the parent factor VIII. Galactose coagulation factor VIII Bos taurus
3 These results suggest that galactose residues are involved in the aggregation of platelets by factor VIII. Galactose coagulation factor VIII Bos taurus