Title : Junctophilin Proteins Tether a Cav1-RyR2-KCa3.1 Tripartite Complex to Regulate Neuronal Excitability.

Pub. Date : 2019 Aug 27

PMID : 31461656






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 JPH3 and JPH4 shRNAs dissociated a Cav1.3-RyR2-KCa3.1 complex and reduced the IsAHP. isahp junctophilin 4 Homo sapiens
2 These data indicate that JPH3 and JPH4 proteins maintain a Cav1-RyR2-KCa3.1 complex that allows two calcium sources to act in tandem to define the activation properties of KCa3.1 channels and the IsAHP. Calcium junctophilin 4 Homo sapiens
3 These data indicate that JPH3 and JPH4 proteins maintain a Cav1-RyR2-KCa3.1 complex that allows two calcium sources to act in tandem to define the activation properties of KCa3.1 channels and the IsAHP. isahp junctophilin 4 Homo sapiens