Pub. Date : 1988 Aug
PMID : 3145408
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Substitution of asparagine for serine at position 17 decreased the affinity of rasH p21 for GTP 20- to 40-fold without significantly affecting its affinity for GDP. | Guanosine Triphosphate | cyclin-dependent kinase inhibitor 1A (P21) | Mus musculus |
| 2 | The inhibitory effect of Asn-17 p21 required its localization to the plasma membrane and was reversed by coexpression of an activated ras gene, indicating that the mutant p21 blocked the endogenous ras function required for NIH 3T3 cell proliferation. | Asparagine | cyclin-dependent kinase inhibitor 1A (P21) | Mus musculus |
| 3 | The inhibitory effect of Asn-17 p21 required its localization to the plasma membrane and was reversed by coexpression of an activated ras gene, indicating that the mutant p21 blocked the endogenous ras function required for NIH 3T3 cell proliferation. | Asparagine | cyclin-dependent kinase inhibitor 1A (P21) | Mus musculus |