Title : Discovery and Characterization of a Cellular Potent Positive Allosteric Modulator of the Polycomb Repressive Complex 1 Chromodomain, CBX7.

Pub. Date : 2019 Oct 17

PMID : 31422906






1 Functional Relationships(s)
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1 A quantitative and target-specific cellular assay was utilized to discover the first potent positive allosteric modulator (PAM) peptidomimetic, UNC4976, of nucleic acid binding by CBX7, a chromodomain methyl-lysine reader of Polycomb repressive complex 1. N(2)-methyl-L-lysine chromobox 7 Homo sapiens