Title : A Transient and Flexible Cation-π Interaction Promotes Hydrolysis of Nucleic Acids in DNA and RNA Nucleases.

Pub. Date : 2019 Jul 10

PMID : 31251587






1 Functional Relationships(s)
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1 Here, extensive classical and quantum-based free-energy molecular simulations show that a cation-pi interaction is transiently formed in situ at the metal core of Bacteriophage-lambda Exonuclease (Exo-lambda), during catalysis. Metals exo Escherichia virus Lambda