Title : Zebrafish neurobehavioral phenomics applied as the behavioral warning methods for fingerprinting endocrine disrupting effect by lead exposure at environmentally relevant level.

Pub. Date : 2019 Sep

PMID : 31132538






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1 Herein, we reported that exposure to Pb at environmentally relevant concentration level (1 mug/L, 10 mug/L and 100 mug/L), disturbed the courtship behavior of adult male zebrafish and further altered the transcriptional patterns of key genes involved in testicular steroidogenesis (igf3, amh, piwil1, lhcgr, fshr, cyp11c1, star, cyp19a1a, cyp19a1b) and apoptosis (bax, cytoC, caspase 9, caspase 3, puma). Lead insulin-like growth factor 3 Danio rerio