Title : Induction of the fibrinogen receptor on human platelets by intracellular mediators.

Pub. Date : 1987 Jan 25

PMID : 3100533






15 Functional Relationships(s)
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1 However, IP3 and Ca2+-induced PAC1 binding were abolished by indomethacin or aspirin, which had no effect on PAC1 binding caused by Gpp(NH)p, phorbol ester, or diacylglycerol. Inositol 1,4,5-Trisphosphate dual specificity phosphatase 2 Homo sapiens
2 However, IP3 and Ca2+-induced PAC1 binding were abolished by indomethacin or aspirin, which had no effect on PAC1 binding caused by Gpp(NH)p, phorbol ester, or diacylglycerol. Indomethacin dual specificity phosphatase 2 Homo sapiens
3 However, IP3 and Ca2+-induced PAC1 binding were abolished by indomethacin or aspirin, which had no effect on PAC1 binding caused by Gpp(NH)p, phorbol ester, or diacylglycerol. Aspirin dual specificity phosphatase 2 Homo sapiens
4 Indeed, we found that the G protein inhibitor guanyl-5"-yl thiophosphate (GDP beta S) inhibited PAC1 binding caused by a thromboxane A2 analog (U46619), IP3, and Ca2+, but had no effect on diacylglycerol or phorbol ester-induced PAC1 binding. guanosine 5'-O-(2-thiodiphosphate) dual specificity phosphatase 2 Homo sapiens
5 Indeed, we found that the G protein inhibitor guanyl-5"-yl thiophosphate (GDP beta S) inhibited PAC1 binding caused by a thromboxane A2 analog (U46619), IP3, and Ca2+, but had no effect on diacylglycerol or phorbol ester-induced PAC1 binding. guanosine 5'-O-(2-thiodiphosphate) dual specificity phosphatase 2 Homo sapiens
6 Indeed, we found that the G protein inhibitor guanyl-5"-yl thiophosphate (GDP beta S) inhibited PAC1 binding caused by a thromboxane A2 analog (U46619), IP3, and Ca2+, but had no effect on diacylglycerol or phorbol ester-induced PAC1 binding. guanosine 5'-O-(2-thiodiphosphate) dual specificity phosphatase 2 Homo sapiens
7 Indeed, we found that the G protein inhibitor guanyl-5"-yl thiophosphate (GDP beta S) inhibited PAC1 binding caused by a thromboxane A2 analog (U46619), IP3, and Ca2+, but had no effect on diacylglycerol or phorbol ester-induced PAC1 binding. guanosine 5'-O-(2-thiodiphosphate) dual specificity phosphatase 2 Homo sapiens
8 Indeed, we found that the G protein inhibitor guanyl-5"-yl thiophosphate (GDP beta S) inhibited PAC1 binding caused by a thromboxane A2 analog (U46619), IP3, and Ca2+, but had no effect on diacylglycerol or phorbol ester-induced PAC1 binding. Thromboxane A2 dual specificity phosphatase 2 Homo sapiens
9 Indeed, we found that the G protein inhibitor guanyl-5"-yl thiophosphate (GDP beta S) inhibited PAC1 binding caused by a thromboxane A2 analog (U46619), IP3, and Ca2+, but had no effect on diacylglycerol or phorbol ester-induced PAC1 binding. 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid dual specificity phosphatase 2 Homo sapiens
10 Indeed, we found that the G protein inhibitor guanyl-5"-yl thiophosphate (GDP beta S) inhibited PAC1 binding caused by a thromboxane A2 analog (U46619), IP3, and Ca2+, but had no effect on diacylglycerol or phorbol ester-induced PAC1 binding. 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid dual specificity phosphatase 2 Homo sapiens
11 Indeed, we found that the G protein inhibitor guanyl-5"-yl thiophosphate (GDP beta S) inhibited PAC1 binding caused by a thromboxane A2 analog (U46619), IP3, and Ca2+, but had no effect on diacylglycerol or phorbol ester-induced PAC1 binding. Inositol 1,4,5-Trisphosphate dual specificity phosphatase 2 Homo sapiens
12 Indeed, we found that the G protein inhibitor guanyl-5"-yl thiophosphate (GDP beta S) inhibited PAC1 binding caused by a thromboxane A2 analog (U46619), IP3, and Ca2+, but had no effect on diacylglycerol or phorbol ester-induced PAC1 binding. Diglycerides dual specificity phosphatase 2 Homo sapiens
13 Indeed, we found that the G protein inhibitor guanyl-5"-yl thiophosphate (GDP beta S) inhibited PAC1 binding caused by a thromboxane A2 analog (U46619), IP3, and Ca2+, but had no effect on diacylglycerol or phorbol ester-induced PAC1 binding. Phorbol Esters dual specificity phosphatase 2 Homo sapiens
14 Thrombin-induced PAC1 binding and phosphoinositide hydrolysis were also inhibited by GDP beta S and by pertussis toxin. guanosine 5'-O-(2-thiodiphosphate) dual specificity phosphatase 2 Homo sapiens
15 Increasing the thrombin concentration overcame the inhibition of PAC1 binding caused by GDP beta S but did not overcome the inhibition of phosphoinositide hydrolysis. guanosine 5'-O-(2-thiodiphosphate) dual specificity phosphatase 2 Homo sapiens