Pub. Date : 2018
PMID : 30662650
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Atorvastatin regulates pericardial patch healing via the microRNA140-ADAM10-ephrinB2 pathway. | Atorvastatin | ephrin B2 | Rattus norvegicus |
| 2 | We hypothesized that atorvastatin attracts ephrinB2-positive cells by regulating the microRNA140-ADAM10-ephrinB2 pathway during patch healing in the arterial environment. | Atorvastatin | ephrin B2 | Rattus norvegicus |
| 3 | We hypothesized that atorvastatin attracts ephrinB2-positive cells by regulating the microRNA140-ADAM10-ephrinB2 pathway during patch healing in the arterial environment. | Atorvastatin | ephrin B2 | Rattus norvegicus |
| 4 | Furthermore, ADAM10 protein expression decreased (P<0.01) and ephrinB2 expression increased (P<0.01) in time- and atorvastatin dose-dependent manner. | Atorvastatin | ephrin B2 | Rattus norvegicus |
| 5 | Conclusion: Atorvastatin regulates neointimal growth after pericardial patch angioplasty; atorvastatin is associated with infiltration of ephrinB2-positive cells, diminished ADAM10 expression, and increased ephrinB2 and miR-140 expression. | Atorvastatin | ephrin B2 | Rattus norvegicus |
| 6 | Conclusion: Atorvastatin regulates neointimal growth after pericardial patch angioplasty; atorvastatin is associated with infiltration of ephrinB2-positive cells, diminished ADAM10 expression, and increased ephrinB2 and miR-140 expression. | Atorvastatin | ephrin B2 | Rattus norvegicus |