Title : USP1 inhibition destabilizes KPNA2 and suppresses breast cancer metastasis.

Pub. Date : 2019 Mar

PMID : 30531833






1 Functional Relationships(s)
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1 Most importantly, pharmacological intervention of USP1 function by pimozide or ML323 significantly represses breast cancer metastasis in mice, suggesting a rationale for using USP1 inhibitors for treatment of patients with breast cancer. ML323 ubiquitin specific peptidase 1 Mus musculus