Title : Druggability of Coronary Artery Disease Risk Loci.

Pub. Date : 2018 Aug

PMID : 30354342






1 Functional Relationships(s)
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1 RESULTS: These pipelines ultimately led to 3 suggestions for drug repurposing: pentolinium, adenosine triphosphate, and riociguat (to target CHRNB4, ACSS2, and GUCY1A3, respectively); and 3 proteins for drug development: LMOD1 (leiomodin 1), HIP1 (huntingtin-interacting protein 1), and PPP2R3A (protein phosphatase 2, regulatory subunit b-double prime, alpha). riociguat cholinergic receptor nicotinic beta 4 subunit Homo sapiens