Title : MT1-MMP as a PET Imaging Biomarker for Pancreas Cancer Management.

Pub. Date : 2018

PMID : 30224904






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The 89Zr-DFO-LEM2/15 probe showed greater specific activity compared to the 68Ga-labelled peptide. Deferoxamine LEM domain nuclear envelope protein 2 Homo sapiens
2 The mean value of tumour uptake for the 89Zr-DFO-LEM2/15 probe (5.67 +- 1.11%ID/g, n=28) was 25-30 times higher than that of the 68Ga-DOTA-AF7p ones. Deferoxamine LEM domain nuclear envelope protein 2 Homo sapiens
3 Tumour/blood ratios (1.13 +- 0.51 and 1.44 +- 0.43 at 5 and 7 days of 89Zr-DFO-LEM2/15 after injection) were higher than those estimated for 68Ga-DOTA-AF7p probes (of approximately tumour/blood ratio = 0.5 at 90 min after injection). Deferoxamine LEM domain nuclear envelope protein 2 Homo sapiens