Title : Prevention of acute liver injury by suppressing plasma kallikrein-dependent activation of latent TGF-β.

Pub. Date : 2018 Oct 12

PMID : 30219233






1 Functional Relationships(s)
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1 Blocking PLK-dependent TGF-beta activation using either the serine proteinase inhibitor FOY305 or the selective PLK inhibitor PKSI-527 or blocking the TGF-beta receptor-mediated signaling pathway using SB431542 significantly prevented Jo2-induced hepatic apoptosis and mortality. camostat kallikrein B, plasma 1 Mus musculus