Pub. Date : 1986 Aug
PMID : 3015383
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | EGF or TPA induced a 4- to 6-fold increase in the phosphorylation of pp17 and a 2- to 4-fold increase in the phosphorylation of pp27, pp34, and pp80 within 15 min after treatment of subconfluent A431 cells. | Tetradecanoylphorbol Acetate | stathmin 1 | Homo sapiens |
| 2 | Alkali treatment of the gels removed most of the incorporated [32P] phosphate from the phosphoproteins, including pp27, pp34, and pp80; however, the phosphoester bond in pp17 was stable to alkaline hydrolysis since there was no removal of [32P]phosphate from this protein. | Phosphorus-32 | stathmin 1 | Homo sapiens |
| 3 | Alkali treatment of the gels removed most of the incorporated [32P] phosphate from the phosphoproteins, including pp27, pp34, and pp80; however, the phosphoester bond in pp17 was stable to alkaline hydrolysis since there was no removal of [32P]phosphate from this protein. | Phosphates | stathmin 1 | Homo sapiens |
| 4 | Treatment of A431 cells with dibutyryl cyclic adenosine 3":5"-monophosphate (1 mM) also increased the phosphorylation of pp17, pp27, and pp34 but not of pp80. | Bucladesine | stathmin 1 | Homo sapiens |
| 5 | Activation of endogenous calcium- and phospholipid-dependent protein kinase C in the cytosol of A431 cells in a cell-free system resulted in the enhanced phosphorylation of pp27, pp34, and pp80 but not of pp17 while exogenous addition of the catalytic subunit of cyclic adenosine 3":5"-monophosphate-dependent protein kinase to cytosol preparations resulted in the phosphorylation of pp17, pp27, and pp34, but not of pp80. | Calcium | stathmin 1 | Homo sapiens |
| 6 | Activation of endogenous calcium- and phospholipid-dependent protein kinase C in the cytosol of A431 cells in a cell-free system resulted in the enhanced phosphorylation of pp27, pp34, and pp80 but not of pp17 while exogenous addition of the catalytic subunit of cyclic adenosine 3":5"-monophosphate-dependent protein kinase to cytosol preparations resulted in the phosphorylation of pp17, pp27, and pp34, but not of pp80. | Calcium | stathmin 1 | Homo sapiens |