Pub. Date : 2016 Oct 31
PMID : 30023485
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We report here on the design, synthesis, and structure-activity relationships of a series of potent peptidomimetic antagonists that were optimized on a trimethyllysine-containing scaffold to target Cbx7. | trimethyllysine | chromobox 7 | Homo sapiens |
| 2 | Our models and binding data suggest that the aromatic cages of Cbx7/Cbx4 can accommodate larger alkyl groups such as diisobutyl substitution on the lysine nitrogen. | Lysine | chromobox 7 | Homo sapiens |
| 3 | Our models and binding data suggest that the aromatic cages of Cbx7/Cbx4 can accommodate larger alkyl groups such as diisobutyl substitution on the lysine nitrogen. | Nitrogen | chromobox 7 | Homo sapiens |