Title : PICK1 inhibits the E3 ubiquitin ligase activity of Parkin and reduces its neuronal protective effect.

Pub. Date : 2018 Jul 24

PMID : 29987020






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The protein levels of several Parkin substrates were reduced in young PICK1-knockout mice, and these mice were resistant to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-mediated toxicity. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine protein interacting with C kinase 1 Mus musculus
2 The protein levels of several Parkin substrates were reduced in young PICK1-knockout mice, and these mice were resistant to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-mediated toxicity. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine protein interacting with C kinase 1 Mus musculus