Title : Neuronatin regulates pancreatic β cell insulin content and secretion.

Pub. Date : 2018 Aug 1

PMID : 29864031






3 Functional Relationships(s)
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1 Here we demonstrate that mice lacking Nnat globally or specifically in beta cells display impaired glucose-stimulated insulin secretion leading to defective glucose handling under conditions of nutrient excess. Glucose neuronatin Mus musculus
2 Here we demonstrate that mice lacking Nnat globally or specifically in beta cells display impaired glucose-stimulated insulin secretion leading to defective glucose handling under conditions of nutrient excess. Glucose neuronatin Mus musculus
3 Loss of neuronatin expression in beta cells therefore reduces insulin content and blunts glucose-stimulated insulin secretion. Glucose neuronatin Mus musculus