Title : Rab34 regulates adhesion, migration, and invasion of breast cancer cells.

Pub. Date : 2018 Jul

PMID : 29622794






4 Functional Relationships(s)
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1 Accordingly, Rab34 is tyrosine phosphorylated by Src at Y247 residue. Tyrosine RAB34, member RAS oncogene family Homo sapiens
2 Importantly, the tyrosine phosphorylation of Rab34 is inhibited in cells in suspension, and increased with the cells re-adhesion. Tyrosine RAB34, member RAS oncogene family Homo sapiens
3 The results uncover a role of Rab34 in migration and invasion of breast cancer cells and its involvement in cancer metastasis, and provide a novel mechanism of tyrosine phosphorylation of Rab34 in regulating cell migration, invasion, and adhesion through modulating the endocytosis, stability, and recycling of integrin beta3. Tyrosine RAB34, member RAS oncogene family Homo sapiens
4 The results uncover a role of Rab34 in migration and invasion of breast cancer cells and its involvement in cancer metastasis, and provide a novel mechanism of tyrosine phosphorylation of Rab34 in regulating cell migration, invasion, and adhesion through modulating the endocytosis, stability, and recycling of integrin beta3. Tyrosine RAB34, member RAS oncogene family Homo sapiens