Pub. Date : 2018 Aug
PMID : 29614330
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Role of the equine CYP3A94, CYP3A95 and CYP3A97 in ketamine metabolism in presence of medetomidine, diazepam and methadone studied by enantioselective capillary electrophoresis. | Ketamine | cytochrome P450 3A97 | Equus caballus |
| 2 | Role of the equine CYP3A94, CYP3A95 and CYP3A97 in ketamine metabolism in presence of medetomidine, diazepam and methadone studied by enantioselective capillary electrophoresis. | Methadone | cytochrome P450 3A97 | Equus caballus |
| 3 | Enzyme kinetics for ketamine N-demethylation were determined using equine CYP3A94, CYP3A95 and CYP3A97, and the effect of medetomidine, diazepam and methadone on the ketamine metabolism was studied in vitro. | Ketamine | cytochrome P450 3A97 | Equus caballus |
| 4 | In contrast to diazepam and methadone, the alpha2-recepor agonist medetomidine diminished the norketamine formation significantly in CYP3A94 and CYP3A97. | Medetomidine | cytochrome P450 3A97 | Equus caballus |
| 5 | In contrast to diazepam and methadone, the alpha2-recepor agonist medetomidine diminished the norketamine formation significantly in CYP3A94 and CYP3A97. | norketamine | cytochrome P450 3A97 | Equus caballus |