Title : Sevoflurane induces liver injury by modulating the expression of insulin-like growth factor 1 via miR-214.

Pub. Date : 2018 Sep

PMID : 29226348






5 Functional Relationships(s)
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1 Sevoflurane induces liver injury by modulating the expression of insulin-like growth factor 1 via miR-214. Sevoflurane microRNA 214 Rattus norvegicus
2 The expression levels of miR-214 in liver cells treated with different concentration of sevoflurane at different time points were detected by qRT-PCR. Sevoflurane microRNA 214 Rattus norvegicus
3 QRT-PCR results suggested that exposure to sevoflurane upregulated the expression level of miR-214 and decreased the concentration of IGF-1 in a dose and time dependent manner. Sevoflurane microRNA 214 Rattus norvegicus
4 Sevoflurane inhibited the expression of IGF-1 through up-regulating miR-214. Sevoflurane microRNA 214 Rattus norvegicus
5 Sevoflurane could induce liver injury by modulating IGF-1 expression via miR-214. Sevoflurane microRNA 214 Rattus norvegicus