Title : The receptor tyrosine kinase EphA2 promotes glutamine metabolism in tumors by activating the transcriptional coactivators YAP and TAZ.

Pub. Date : 2017 Dec 5

PMID : 29208682






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 We found that the receptor tyrosine kinase EphA2 activated the TEAD family transcriptional coactivators YAP and TAZ (YAP/TAZ), likely in a ligand-independent manner, to promote glutamine metabolism in cells and mouse models of HER2-positive breast cancer. Glutamine tafazzin, phospholipid-lysophospholipid transacylase Mus musculus
2 We found that the receptor tyrosine kinase EphA2 activated the TEAD family transcriptional coactivators YAP and TAZ (YAP/TAZ), likely in a ligand-independent manner, to promote glutamine metabolism in cells and mouse models of HER2-positive breast cancer. Glutamine tafazzin, phospholipid-lysophospholipid transacylase Mus musculus