Title : Everolimus Plus Ku0063794 Regimen Promotes Anticancer Effects against Hepatocellular Carcinoma Cells through the Paradoxical Inhibition of Autophagy.

Pub. Date : 2018 Jul

PMID : 29121714






3 Functional Relationships(s)
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1 Materials and Methods: We compared the effects of everolimus and Ku0063794, individually or in combination, on both the in vitro and in vivo models of HCCs. Everolimus holocytochrome c synthetase Mus musculus
2 Conclusion: The combination of everolimus and Ku0063794 potentiates anticancer effects on HCCs through a decrease in autophagy, which is prompted by SIRT1 downregulation. Everolimus holocytochrome c synthetase Mus musculus
3 Conclusion: The combination of everolimus and Ku0063794 potentiates anticancer effects on HCCs through a decrease in autophagy, which is prompted by SIRT1 downregulation. Ku 0063794 holocytochrome c synthetase Mus musculus