Pub. Date : 1988
PMID : 2905962
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Ramipril inhibition of rabbit (Oryctolagus cuniculus) small intestinal brush border membrane angiotensin converting enzyme. | Ramipril | angiotensin-converting enzyme | Oryctolagus cuniculus |
| 2 | Hydrolysis kinetics of rabbit intestinal ACE were comparable to the lung, utilizing the substrate (N-[3-(2-furyl)acryloyl]-L-phenylalanylglycylglycine; the Vmax = 543 +/- 51 mumol/min/g and Km = 0.62 +/- 0.09 mmol/l. | n-[3-(2-furyl)acryloyl]-l-phenylalanylglycylglycine | angiotensin-converting enzyme | Oryctolagus cuniculus |
| 3 | Intestinal brush border ACE activity was strongly inhibited by the antihypertensive drug Ramipril, which yielded an IC50 value of 5 nmol/l; the ACE activity remained completely inhibited during 15 days after a single dose of 10 mumol/l Ramipril. | Ramipril | angiotensin-converting enzyme | Oryctolagus cuniculus |
| 4 | Intestinal brush border ACE activity was strongly inhibited by the antihypertensive drug Ramipril, which yielded an IC50 value of 5 nmol/l; the ACE activity remained completely inhibited during 15 days after a single dose of 10 mumol/l Ramipril. | Ramipril | angiotensin-converting enzyme | Oryctolagus cuniculus |
| 5 | Intestinal brush border ACE activity was strongly inhibited by the antihypertensive drug Ramipril, which yielded an IC50 value of 5 nmol/l; the ACE activity remained completely inhibited during 15 days after a single dose of 10 mumol/l Ramipril. | Ramipril | angiotensin-converting enzyme | Oryctolagus cuniculus |
| 6 | Intestinal brush border ACE activity was strongly inhibited by the antihypertensive drug Ramipril, which yielded an IC50 value of 5 nmol/l; the ACE activity remained completely inhibited during 15 days after a single dose of 10 mumol/l Ramipril. | Ramipril | angiotensin-converting enzyme | Oryctolagus cuniculus |