Pub. Date : 2017 Oct
PMID : 28731156
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The present study demonstrated that glutamate-induced exocytosis was increased in beta cells derived from PICK1-knockout mice. | Glutamic Acid | protein interacting with C kinase 1 | Mus musculus |
2 | In agreement with this result, adding PICK1 in beta cells reduced glutamate-induced exocytosis, whereas adding EVKI, a peptide that interrupts the interaction between AMPARs and PICK1, increased the exocytosis of beta cells with the application of glutamate. | Glutamic Acid | protein interacting with C kinase 1 | Mus musculus |
3 | Taken together, the results indicate that PICK1 regulates glutamate-induced exocytosis in beta cells. | Glutamic Acid | protein interacting with C kinase 1 | Mus musculus |