Pub. Date : 2017 Dec
PMID : 28631291
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Among the findings, there was a significant association between folic acid concentration and hsa-let-7 g methylation level in NTD cases. | Folic Acid | microRNA let-7g | Homo sapiens |
2 | Overexpression of hsa-let-7 g, along with its target genes, disturbed the migration and proliferation of SK-N-SH cells, implying that hsa-let-7 g plays important roles in the prevention of NTDs by folic acid. | Folic Acid | microRNA let-7g | Homo sapiens |
3 | Overexpression of hsa-let-7 g, along with its target genes, disturbed the migration and proliferation of SK-N-SH cells, implying that hsa-let-7 g plays important roles in the prevention of NTDs by folic acid. | Folic Acid | microRNA let-7g | Homo sapiens |
4 | In summary, our data suggest a relationship between aberrant methylation of hsa-let-7 g and disturbed folate metabolism in NTDs, implying that improvements in nutrition during early pregnancy may prevent such defects, possibly via the donation of methyl groups for miRNAs. | Folic Acid | microRNA let-7g | Homo sapiens |