Title : Nerve growth factor-induced transformation of immature chromaffin cells in vivo into sympathetic neurons: effect of antiserum to nerve growth factor.

Pub. Date : 1979 Mar

PMID : 286308






2 Functional Relationships(s)
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1 Pre- and postnatal injections of nerve growth factor, initiated with one dose on day 17 of gestation and continued after birth with daily subcutaneous administration until day 10 of life, produce massive transformation of chromaffin in sympathetic nerve cells in the rat adrenal medulla. chromaffin myotrophin Rattus norvegicus
2 When the growth factor treatment is initiated after birth, only a partial replacement of chromaffin with nerve cells takes place. chromaffin myotrophin Rattus norvegicus