Pub. Date : 1988
PMID : 2849744
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Phorbol 12,13-dibutyrate, a protein kinase C (PKC) activator, and permeable c-AMP derivatives, which activate protein kinase A (PKA), stimulated phosphorylation of K-ras(4B) p21 in 416B cells 3 to 5 fold. | Phorbol 12,13-Dibutyrate | cyclin-dependent kinase inhibitor 1A (P21) | Mus musculus |
| 2 | Phorbol 12,13-dibutyrate, a protein kinase C (PKC) activator, and permeable c-AMP derivatives, which activate protein kinase A (PKA), stimulated phosphorylation of K-ras(4B) p21 in 416B cells 3 to 5 fold. | c-amp | cyclin-dependent kinase inhibitor 1A (P21) | Mus musculus |
| 3 | By tryptic peptide mapping, it was found that both PKC and PKA phosphorylated in vitro the K-ras p21 at the same site as was found in p21 from cells labeled with [32P]orthophosphate in vivo. | Peptides | cyclin-dependent kinase inhibitor 1A (P21) | Mus musculus |
| 4 | By tryptic peptide mapping, it was found that both PKC and PKA phosphorylated in vitro the K-ras p21 at the same site as was found in p21 from cells labeled with [32P]orthophosphate in vivo. | Phosphorus-32 | cyclin-dependent kinase inhibitor 1A (P21) | Mus musculus |
| 5 | By tryptic peptide mapping, it was found that both PKC and PKA phosphorylated in vitro the K-ras p21 at the same site as was found in p21 from cells labeled with [32P]orthophosphate in vivo. | Phosphates | cyclin-dependent kinase inhibitor 1A (P21) | Mus musculus |
| 6 | By tryptic peptide mapping, it was found that both PKC and PKA phosphorylated in vitro the K-ras p21 at the same site as was found in p21 from cells labeled with [32P]orthophosphate in vivo. | Phosphates | cyclin-dependent kinase inhibitor 1A (P21) | Mus musculus |
| 7 | The construction of a mutant by site-directed mutagenesis allowed the identification of serine-177 as the phosphorylation site of H-ras p21. | Serine | cyclin-dependent kinase inhibitor 1A (P21) | Mus musculus |