Pub. Date : 2017 Apr
PMID : 28484611
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Transcriptional response of Hoxb genes to retinoid signalling is regionally restricted along the neural tube rostrocaudal axis. | Retinoids | homeobox B cluster | Mus musculus |
| 2 | Correlating with these effects, key RA-responsive regulatory regions in the Hoxb cluster displayed opposite enrichment of activating or repressing histone marks in rostral and caudal NSPCs. | Tretinoin | homeobox B cluster | Mus musculus |
| 3 | Finally, RA was able to strengthen Hoxb chromatin activation in caudal NSPCs, but was ineffective on the repressed Hoxb chromatin of rostral NSPCs. | Tretinoin | homeobox B cluster | Mus musculus |