Title : Positional Scanning Identifies the Molecular Determinants of a High Affinity Multi-Leucine Inhibitor for Furin and PACE4.

Pub. Date : 2017 Apr 13

PMID : 28287731






1 Functional Relationships(s)
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1 Herein, the molecular determinants for PACE4 and furin inhibition were investigated by positional scanning using peptide libraries that substituted its leucine core with each natural amino acid. Leucine proprotein convertase subtilisin/kexin type 6 Homo sapiens