Pub. Date : 1987 Apr 15
PMID : 2820381
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Activation of phospholipase C associated with isolated rabbit platelet membranes by guanosine 5"-[gamma-thio]triphosphate and by thrombin in the presence of GTP. | Guanosine 5'-O-(3-Thiotriphosphate) | LOC100009319 | Oryctolagus cuniculus |
| 2 | Activation of phospholipase C associated with isolated rabbit platelet membranes by guanosine 5"-[gamma-thio]triphosphate and by thrombin in the presence of GTP. | Guanosine Triphosphate | LOC100009319 | Oryctolagus cuniculus |
| 3 | Addition of unlabelled IP3 to trap [3H]IP3 before it was degraded to [3H]IP2 showed that only about 20% of the additional [3H]inositol phosphates that accumulated with GTP[S] or thrombin and GTP were derived from the action of phospholipase C on [3H]PIP2. | Inositol 1,4,5-Trisphosphate | LOC100009319 | Oryctolagus cuniculus |
| 4 | The results provide further evidence that guanine-nucleotide-binding protein mediates signal transduction between the thrombin receptor and phospholipase C, and suggest that PIP may be a major substrate of this enzyme in the platelet. | Guanine Nucleotides | LOC100009319 | Oryctolagus cuniculus |