Title : Cytotoxicity of trans-chalcone and licochalcone A against breast cancer cells is due to apoptosis induction and cell cycle arrest.

Pub. Date : 2017 Jan

PMID : 27903423






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 However, only trans-chalcone induced the expression of the CIDEA gene and protein in these two experiments. Chalcone cell death-inducing DNA fragmentation factor, alpha subunit-like effector A Mus musculus
2 Furthermore, transient transfections of MCF-7 using a construction of a promoter-luciferase vector showed that trans-chalcone induced the expression of the CIDEA promoter activity in 24 and 48h. Chalcone cell death-inducing DNA fragmentation factor, alpha subunit-like effector A Mus musculus
3 In conclusion, the results showed that trans-chalcone promoted high induction of the CIDEA promoter gene and protein, which is related to DNA fragmentation during apoptosis. Chalcone cell death-inducing DNA fragmentation factor, alpha subunit-like effector A Mus musculus