Title : Loss-of-function of an Arabidopsis NADPH pyrophosphohydrolase, AtNUDX19, impacts on the pyridine nucleotides status and confers photooxidative stress tolerance.

Pub. Date : 2016 Nov 22

PMID : 27874073






6 Functional Relationships(s)
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Protein Name
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1 Loss-of-function of an Arabidopsis NADPH pyrophosphohydrolase, AtNUDX19, impacts on the pyridine nucleotides status and confers photooxidative stress tolerance. pyridine nucleotides nudix hydrolase homolog 19 Arabidopsis thaliana
2 An Arabidopsis Nudix hydrolase, AtNUDX19, was previously identified to have NADPH hydrolytic activity in vitro, suggesting this enzyme to be a regulator of the NADPH status. NADP nudix hydrolase homolog 19 Arabidopsis thaliana
3 An Arabidopsis Nudix hydrolase, AtNUDX19, was previously identified to have NADPH hydrolytic activity in vitro, suggesting this enzyme to be a regulator of the NADPH status. NADP nudix hydrolase homolog 19 Arabidopsis thaliana
4 NADPH levels were increased in nudx19 mutants under both normal and high light conditions, while NADP+ and NAD+ levels were decreased. NADP nudix hydrolase homolog 19 Arabidopsis thaliana
5 Despite the high redox states of NADP(H), nudx19 mutants exhibited high tolerance to moderate light- or methylviologen-induced photooxidative stresses. NADP nudix hydrolase homolog 19 Arabidopsis thaliana
6 Indeed, nudx19 mutants accumulated SA and showed high sensitivity to the hormone. Salicylic Acid nudix hydrolase homolog 19 Arabidopsis thaliana