Title : Leukocyte immunoglobulin-like receptor B4 regulates key signalling molecules involved in FcγRI-mediated clathrin-dependent endocytosis and phagocytosis.

Pub. Date : 2016 Oct 11

PMID : 27725776






3 Functional Relationships(s)
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1 We proposed the leukocyte immunoglobulin-like receptor B4 (LILRB4) that inhibits FcgammaRI-mediated cytokine production via Tyr dephosphorylation of multiple kinases, may also regulate endocytosis/phagocytosis through similar mechanisms. Tyrosine leukocyte immunoglobulin like receptor B4 Homo sapiens
2 We proposed the leukocyte immunoglobulin-like receptor B4 (LILRB4) that inhibits FcgammaRI-mediated cytokine production via Tyr dephosphorylation of multiple kinases, may also regulate endocytosis/phagocytosis through similar mechanisms. Tyrosine leukocyte immunoglobulin like receptor B4 Homo sapiens
3 These results suggest that Tyr phosphorylation may be critical in FcgammaRI-dependent endocytosis/phagocytosis that may be regulated by LILRB4 by triggering dephosphorylation of key signalling proteins. Tyrosine leukocyte immunoglobulin like receptor B4 Homo sapiens