Title : A critical role for NF2 and the Hippo pathway in branching morphogenesis.

Pub. Date : 2016 Aug 2

PMID : 27480037






2 Functional Relationships(s)
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1 Conversely, Yap/Taz UB-deletion leads to cyst-like branching and expansion of UB tip markers, suggesting a shift towards tip cell identity. BM tafazzin, phospholipid-lysophospholipid transacylase Mus musculus
2 Based on these data we propose that NF2 and the Hippo pathway locally repress YAP/TAZ activity in the UB to promote subsequent splitting of the tip to allow branching morphogenesis. BM tafazzin, phospholipid-lysophospholipid transacylase Mus musculus