Title : Cbx7 is epigenetically silenced in glioblastoma and inhibits cell migration by targeting YAP/TAZ-dependent transcription.

Pub. Date : 2016 Jun 13

PMID : 27291091






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Bisulphite sequencing and methylation inhibitor treatment established the hypermethylation of Cbx7 in GBM. hydrogen sulfite chromobox 7 Homo sapiens
2 GSEA of Cbx7 regulated genes identified Cbx7 as a repressor of transcription co-activators YAP/TAZ, the inhibitory targets of the Hippo signalling pathway. gsea chromobox 7 Homo sapiens
3 GSEA of Cbx7 regulated genes identified Cbx7 as a repressor of transcription co-activators YAP/TAZ, the inhibitory targets of the Hippo signalling pathway. gsea chromobox 7 Homo sapiens