Title : Methylation of miR-145a-5p promoter mediates adipocytes differentiation.

Pub. Date : 2016 Jun 17

PMID : 27179777






4 Functional Relationships(s)
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1 Overexpression or inhibition of miR-145a-5p was unfavorable or beneficial, respectively, for adipogenesis, and these effects were achieved by regulating adipocyte-specific genes involved in lipogenic transcription, fatty acid synthesis, and fatty acid transportation. Fatty Acids microRNA 615 Mus musculus
2 Overexpression or inhibition of miR-145a-5p was unfavorable or beneficial, respectively, for adipogenesis, and these effects were achieved by regulating adipocyte-specific genes involved in lipogenic transcription, fatty acid synthesis, and fatty acid transportation. Fatty Acids microRNA 615 Mus musculus
3 Surprisingly, the miR-145a-5p-repressed adipocyte differentiation was enhanced or rescued when cells treated with 5-Aza-dC were transfected with miR-145a-5p mimics or inhibitors, respectively. Decitabine microRNA 615 Mus musculus
4 Surprisingly, the miR-145a-5p-repressed adipocyte differentiation was enhanced or rescued when cells treated with 5-Aza-dC were transfected with miR-145a-5p mimics or inhibitors, respectively. Decitabine microRNA 615 Mus musculus