Title : Autophagy Is Involved in the Sevoflurane Anesthesia-Induced Cognitive Dysfunction of Aged Rats.

Pub. Date : 2016

PMID : 27111854






1 Functional Relationships(s)
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1 Rapamycin treatment led to the rapid accumulation of autophagic bodies and autophagy lysosomes, decreased p62 protein levels, and increased the ratio of microtubule-associated protein light chain 3 II (LC3-II) to LC3-I in hippocampal neurons through the mTOR signaling pathway. Sirolimus KH RNA binding domain containing, signal transduction associated 1 Rattus norvegicus