Title : Targeted proteomics identify metabolism-dependent interactors of yeast cytochrome c peroxidase: implications in stress response and heme trafficking.

Pub. Date : 2016 Apr

PMID : 26980054






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 When cells switch their metabolism from fermentation to respiration mitochondrial H2O2 levels spike, and overoxidation of its polypeptide labilizes Ccp1"s heme. Heme cytochrome-c peroxidase Saccharomyces cerevisiae S288C
2 A large pool of heme-free Ccp1 exits the mitochondria and enters the nucleus and vacuole. Heme cytochrome-c peroxidase Saccharomyces cerevisiae S288C
3 These new interactors expand the scope of Ccp1"s possible roles in stress response and in heme trafficking and suggest several new lines of investigation. Heme cytochrome-c peroxidase Saccharomyces cerevisiae S288C