Pub. Date : 1989 Nov
PMID : 2682656
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | An oncogenic 21-kDa (p21) protein (Harvey RAS protein with Val-12) has been covalently modified with a functional reagent that contains a photoactivatable aromatic azide group. | Valine | cyclin-dependent kinase inhibitor 1A (P21) | Mus musculus |
| 2 | An oncogenic 21-kDa (p21) protein (Harvey RAS protein with Val-12) has been covalently modified with a functional reagent that contains a photoactivatable aromatic azide group. | Azides | cyclin-dependent kinase inhibitor 1A (P21) | Mus musculus |
| 3 | To identify the putative intracellular protein(s) that specifically interact with the modified p21 protein, the cells were pulsed with [35S]methionine at selected times after fusion and then UV-irradiated to activate the azide group. | Sulfur-35 | cyclin-dependent kinase inhibitor 1A (P21) | Mus musculus |
| 4 | To identify the putative intracellular protein(s) that specifically interact with the modified p21 protein, the cells were pulsed with [35S]methionine at selected times after fusion and then UV-irradiated to activate the azide group. | Methionine | cyclin-dependent kinase inhibitor 1A (P21) | Mus musculus |
| 5 | To identify the putative intracellular protein(s) that specifically interact with the modified p21 protein, the cells were pulsed with [35S]methionine at selected times after fusion and then UV-irradiated to activate the azide group. | Azides | cyclin-dependent kinase inhibitor 1A (P21) | Mus musculus |
| 6 | The resulting nitrene covalently binds to amino acid residues in adjacent proteins, thus linking the p21 protein to these proteins. | phenylnitrene | cyclin-dependent kinase inhibitor 1A (P21) | Mus musculus |