Title : MPV17 Loss Causes Deoxynucleotide Insufficiency and Slow DNA Replication in Mitochondria.

Pub. Date : 2016 Jan

PMID : 26760297






2 Functional Relationships(s)
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1 In Mpv17 ablated mice, liver mitochondria showed substantial decreases in the levels of dGTP and dTTP and severe mitochondrial DNA depletion, whereas the dNTP pool was not significantly altered in kidney and brain mitochondria that had near normal levels of DNA. deoxyguanosine triphosphate MpV17 mitochondrial inner membrane protein Mus musculus
2 In Mpv17 ablated mice, liver mitochondria showed substantial decreases in the levels of dGTP and dTTP and severe mitochondrial DNA depletion, whereas the dNTP pool was not significantly altered in kidney and brain mitochondria that had near normal levels of DNA. thymidine 5'-triphosphate MpV17 mitochondrial inner membrane protein Mus musculus