Pub. Date : 2016 Jan 18
PMID : 26636774
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The challenging protein, 125-residue human phosphohistidine phosphatase 1 (PHPT1), has three cysteines near the C-terminus, which are not strategically placed for ligation. | Cysteine | phosphohistidine phosphatase 1 | Homo sapiens |
| 2 | The challenging protein, 125-residue human phosphohistidine phosphatase 1 (PHPT1), has three cysteines near the C-terminus, which are not strategically placed for ligation. | Cysteine | phosphohistidine phosphatase 1 | Homo sapiens |
| 3 | PHPT1 was prepared from three unprotected peptide segments using two ligation reactions at cysteine and alanine junctions. | Cysteine | phosphohistidine phosphatase 1 | Homo sapiens |
| 4 | PHPT1 was prepared from three unprotected peptide segments using two ligation reactions at cysteine and alanine junctions. | Alanine | phosphohistidine phosphatase 1 | Homo sapiens |
| 5 | This approach was used to synthesize both the wild-type PHPT1 and an analogue in which the active-site histidine was substituted with the unnatural and isosteric amino acid beta-thienyl-l-alanine. | Histidine | phosphohistidine phosphatase 1 | Homo sapiens |
| 6 | This approach was used to synthesize both the wild-type PHPT1 and an analogue in which the active-site histidine was substituted with the unnatural and isosteric amino acid beta-thienyl-l-alanine. | beta-thienyl-l-alanine | phosphohistidine phosphatase 1 | Homo sapiens |