Title : The Hippo pathway effectors YAP and TAZ promote cell growth by modulating amino acid signaling to mTORC1.

Pub. Date : 2015 Dec

PMID : 26611634






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Deletion of YAP/TAZ abolishes expression of LAT1 and reduces leucine uptake. Leucine tafazzin, phospholipid-lysophospholipid transacylase Mus musculus
2 Re-expression of SLC7A5 in YAP/TAZ knockout cells restores leucine uptake and mTORC1 activation. Leucine tafazzin, phospholipid-lysophospholipid transacylase Mus musculus